The median indwelling time of pulmonary arterial catheters is 1.9 days. Echocardiography, CT and MRT are point measurements which cannot guide continuous data driven therapy. Only CorLog enables wireless continuous measurement.
2022 – CorLog publication
CorLog related summary: The continuous long-term registration of right ventricular systolic pressure by an ultrathin probe in patients with PH is for several reasons of special interest: first, transthoracic echocardiography substantially underestimated in 60% of patients with PH the true RVSP and PAP measured by right heart catheterization, and second, a pulmonary artery catheter because of its wide range of complications can be left in place only for few days. Thus, continuous long-term monitoring of RVSP and ePAD is the only way for reliable detection and treatment of right ventricular hypertension, PH and consecutive changes in RVEF.
Journal: Pulmonary Circulation
DOI: 10.1002/pul2.12179
Type:
Retrospective, single center study
N:
39
2022 – CorLog publication
CorLog related summary: In our opinion, the described method is an elegant and promising approach for monitoring
RV function and response to treatment by PV loop analysis. PV loops can be created at will
by performing three-dimensional echocardiography, avoiding further invasive procedures for
the patient.
Journal: Circulation: Heart Failure
DOI: 10.1161/CIRCHEARTFAILURE.122.010097
Type:
Case report
N:
1
2022
CorLog related summary: PH-HFpEF is a growing epidemic with high morbidity and mortality and no treatment. The clear unmet need and lethal nature of PH-HFpEF must be met with novel solutions at all levels of therapeutic development.
Journal: Circulation
Type:
Science Advisory
N:
–
2022
CorLog related summary: In HFpEF, exercise intolerance is a hallmark manifestation, characterized by impairment in the physiological reserve capacity of multiple organ systems that is the cardiac dynamics itself and/or related comorbid conditions and extracardiac factors. The relative cardiac and extracardiac deficits vary among individuals. Therefore, detailed measurements made during exercise are necessary to identify and rank-order the multiorgan system limitations in exercise reserve capacity.
Journal: European Journal of Heart Failure
DOI: 10.1002/ejhf.2601
Type:
Clinical consensus statement
N:
–
2021 – CorLog publication
CorLog related summary: Thus, insertion of an ultrathin probe into the right ventricle seems to be the only way of continuous long-term monitoring of right ventricular and pulmonary artery pressures for reliable detection and treatment of right ventricular hypertension and PAH.
Journal: ESC HF
DOI: 10.1002/ehf2.13600
Type:
Retrospective, single center study
N:
30
2020
CorLog related summary: RV dysfunction is an independent determinant on survival in patients with all forms of PH.
Journal: Cardiovascular diagnosis and therapy
DOI: 10.21037/cdt-20-479
Type:
Meta analysis
N:
3300
2020
CorLog related summary: Use of complete PAC-derived hemodynamic data prior to MCS initiation is associated with improved survival from CS.
Journal: JACC – Heart Failure
DOI: 10.1016/j.jchf.2020.08.012
Type:
Retrospective, multicenter
N:
1414
2019
CorLog related summary: In patients with pulmonary hypertension, the adaptation of the right ventricle to the increase in afterload (RV–arterial coupling) is a key determinant of outcome. […] Given the prognostic relevance of RV–arterial coupling in pulmonary hypertension, simplified methods to assess RV–arterial coupling should be validated and incorporated into routine clinical follow-up and future clinical trials.
Journal: British Journal of Pharmacology
DOI: 10.1111/bph.14866
Type:
Meta analysis
N:
–
2017
CorLog related summary: Baseline ePAD is a predictor of mortality, independent of other covariates that have previously been demonstrated to predict mortality. Change in ePAD, from baseline to 6 months was associated with changes in subsequent mortality rate; this relationship is durable.
Journal: Circulation – Heart Failure
DOI: 10.1161/CIRCHEARTFAILURE.116.003594
Type:
Prospective, randomized, multicenter
N:
790
2013
CorLog related summary: Doppler echocardiography allows for accurate measurements of the pulmonary circulation, but with moderate precision, which explains why the procedure is valid for population studies but cannot be used for the individual diagnosis of pulmonary hypertension.
Journal:International Journal of Cardiology
DOI: 10.1016/j.ijcard.2013.07.005
Type:
Prospective, single center study
N:
152
2005
CorLog related summary: Median indwelling time of pulmonary arterial catheters was 1.9 days.
Journal: JAMA
DOI: 10.1001/jama.294.13.1625
Type:
Prospective, randomized, multicenter
N:
433
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