CorLog is the only removable hemodynamic monitor that can continuously measure up to 30 days.

The median indwelling time of pulmonary arterial catheters is 1.9 days. Echocardiography, CT and MRT are point measurements which cannot guide continuous data driven therapy. Only CorLog enables wireless continuous measurement.

2022 – CorLog publication

Pressure based beat-to-beat right ventricular ejection fraction and Tau from continuous measured ventricular pressures in COVID-19 ARDS patients

CorLog related summary: The continuous long-term registration of right ventricular systolic pressure by an ultrathin probe in patients with PH is for several reasons of special interest: first, transthoracic echocardiography substantially underestimated in 60% of patients with PH the true RVSP and PAP measured by right heart catheterization, and second, a pulmonary artery catheter because of its wide range of complications can be left in place only for few days. Thus, continuous long-term monitoring of RVSP and ePAD is the only way for reliable detection and treatment of right ventricular hypertension, PH and consecutive changes in RVEF.

Journal: Pulmonary Circulation
DOI: 10.1002/pul2.12179

Type:

Retrospective, single center study

2022 – CorLog publication

Monitoring of Right Ventricular Failure with Daily Pressure-Volume Loops Obtained via an App and
Three-Dimensional Echocardiography

CorLog related summary: In our opinion, the described method is an elegant and promising approach for monitoring
RV function and response to treatment by PV loop analysis. PV loops can be created at will
by performing three-dimensional echocardiography, avoiding further invasive procedures for
the patient.

Journal: Circulation: Heart Failure
DOI: 10.1161/CIRCHEARTFAILURE.122.010097

Type:
Case report

N:
1

2022

Elucidating the Clinical Implications and Pathophysiology of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction: A Call to Action

CorLog related summary: PH-HFpEF is a growing epidemic with high morbidity and mortality and no treatment. The clear unmet need and lethal nature of PH-HFpEF must be met with novel solutions at all levels of therapeutic development.

Journal: Circulation

DOI: 10.1161/CIR.0000000000001079

Type:
Science Advisory

N:
–

2022

Exercise testing in heart failure with preserved ejection fraction: an appraisal through diagnosis, pathophysiology and therapy

CorLog related summary: In HFpEF, exercise intolerance is a hallmark manifestation, characterized by impairment in the physiological reserve capacity of multiple organ systems that is the cardiac dynamics itself and/or related comorbid conditions and extracardiac factors. The relative cardiac and extracardiac deficits vary among individuals. Therefore, detailed measurements made during exercise are necessary to identify and rank-order the multiorgan system limitations in exercise reserve capacity.

Journal: European Journal of Heart Failure
DOI: 10.1002/ejhf.2601

Type:
Clinical consensus statement

N:
–

2021 – CorLog publication

Continuous long-term wireless measurement of right ventricular pressures and estimated diastolic pulmonary artery pressure in patients with severe COVID-19 acute respiratory distress syndrome

CorLog related summary: Thus, insertion of an ultrathin probe into the right ventricle seems to be the only way of continuous long-term monitoring of right ventricular and pulmonary artery pressures for reliable detection and treatment of right ventricular hypertension and PAH.

Journal: ESC HF
DOI: 10.1002/ehf2.13600

Type:
Retrospective, single center study

N:
30

2020

Mechanics of right ventricular dysfunction in pulmonary arterial hypertension and heart failure with preserved ejection fraction

CorLog related summary: RV dysfunction is an independent determinant on survival in patients with all forms of PH.

Journal: Cardiovascular diagnosis and therapy
DOI: 10.21037/cdt-20-479

Type:
Meta analysis

N:
3300

2020

Complete Hemodynamic Profiling With Pulmonary Artery Catheters in Cardiogenic Shock Is Associated With Lower In-Hospital Mortality

CorLog related summary: Use of complete PAC-derived hemodynamic data prior to MCS initiation is associated with improved survival from CS.

Journal: JACC – Heart Failure
DOI: 10.1016/j.jchf.2020.08.012

Type:
Retrospective, multicenter

N:
1414

2019

Right heart failure in pulmonary hypertension: Diagnosis and new perspectives on vascular and direct right ventricular treatment

CorLog related summary: In patients with pulmonary hypertension, the adaptation of the right ventricle to the increase in afterload (RV–arterial coupling) is a key determinant of outcome. […] Given the prognostic relevance of RV–arterial coupling in pulmonary hypertension, simplified methods to assess RV–arterial coupling should be validated and incorporated into routine clinical follow-up and future clinical trials.

Journal: British Journal of Pharmacology
DOI: 10.1111/bph.14866

Type:
Meta analysis

N:
–

2017

Intracardiac Pressures Measured Using an Implantable Hemodynamic Monitor

CorLog related summary: Baseline ePAD is a predictor of mortality, independent of other covariates that have previously been demonstrated to predict mortality. Change in ePAD, from baseline to 6 months was associated with changes in subsequent mortality rate; this relationship is durable.

Journal: Circulation – Heart Failure
DOI: 10.1161/CIRCHEARTFAILURE.116.003594

Type:
Prospective, randomized, multicenter

N:
790

2013

Accuracy and precision of echocardiography versus right heart catheterization for the assessment of pulmonary hypertension

CorLog related summary: Doppler echocardiography allows for accurate measurements of the pulmonary circulation, but with moderate precision, which explains why the procedure is valid for population studies but cannot be used for the individual diagnosis of pulmonary hypertension.

Journal:International Journal of Cardiology
DOI: 10.1016/j.ijcard.2013.07.005

Type:
Prospective, single center study

N:
152

2005

Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness

CorLog related summary: Median indwelling time of pulmonary arterial catheters was 1.9 days.

Journal: JAMA
DOI: 10.1001/jama.294.13.1625

Type:
Prospective, randomized, multicenter

N:
433

CorLog is the only removable hemodynamic monitor that can continuously measure up to 30 days.

Pressure based beat-to-beat right ventricular ejection fraction and Tau from continuous measured ventricular pressures in COVID-19 ARDS patients

Monitoring of Right Ventricular Failure with Daily Pressure-Volume Loops Obtained via an App and Three-Dimensional Echocardiography

Elucidating the Clinical Implications and Pathophysiology of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction: A Call to Action

Exercise testing in heart failure with preserved ejection fraction: an appraisal through diagnosis, pathophysiology and therapy

Continuous long-term wireless measurement of right ventricular pressures and estimated diastolic pulmonary artery pressure in patients with severe COVID-19 acute respiratory distress syndrome

Mechanics of right ventricular dysfunction in pulmonary arterial hypertension and heart failure with preserved ejection fraction

Complete Hemodynamic Profiling With Pulmonary Artery Catheters in Cardiogenic Shock Is Associated With Lower In-Hospital Mortality

Right heart failure in pulmonary hypertension: Diagnosis and new perspectives on vascular and direct right ventricular treatment

Intracardiac Pressures Measured Using an Implantable Hemodynamic Monitor

Accuracy and precision of echocardiography versus right heart catheterization for the assessment of pulmonary hypertension

Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness

Monitoring of Right Ventricular Failure with Daily Pressure-Volume Loops Obtained via an App and
Three-Dimensional Echocardiography