CorLog is the only removable hemodynamic monitor that can continuously measure up to 30 days.
The median indwelling time of pulmonary arterial catheters is 1.9 days. Echocardiography, CT and MRT are point measurements which cannot guide continuous data driven therapy. Only CorLog enables wireless continuous measurement.
2023 – CorLog publication
First in human implantation of the CorLog device for postoperative intravascular pressure sensing in left ventricular assist device patients
CorLog related summary: The first-in-human clinical application of permanent wireless pressure monitoring in an LVAD patient has proven the feasibility of the device as well as the safe and continuous detection of hemodynamic parameters. This new technology offers a viable and needed option for wireless, continuous right heart monitoring in heart failure patients for the first 30 days after LVAD implantation.
Journal: Artificial Organs
DOI: 10.1111/aor.14690
Type:
Case report
N:
1
2023 – CorLog publication
AHA23 - Cardiopulmonary Best Abstract Award: Pausing Reveals Exercise-Induced Uncoupling: Exploring the Dynamics of RV-PA Coupling in the Six-Minute Walking Test
CorLog related summary: This is the first investigation into the significance of RV-PA coupling in real-life exercise limitation and dyspnea during the 6MWT. Pauses observed during the 6MWT can serve as indicators of exercise-induced uncoupling. We used a wireless hemodynamic monitoring system (CorLog, emka-medical, Germany) to continuously measure right ventricular pressure in 10 patients with PH (8 = group I, 1 = III, 1 = IV) during a 6MWT.
Journal: Circulation/AHA23
DOI: 10.1161/circ.148.suppl_1.15449
Type:
Case report
N:
10
2022 – CorLog publication
Pressure based beat-to-beat right ventricular ejection fraction and Tau from continuous measured ventricular pressures in COVID-19 ARDS patients
CorLog related summary: The continuous long-term registration of right ventricular systolic pressure by an ultrathin probe in patients with PH is for several reasons of special interest: first, transthoracic echocardiography substantially underestimated in 60% of patients with PH the true RVSP and PAP measured by right heart catheterization, and second, a pulmonary artery catheter because of its wide range of complications can be left in place only for few days. Thus, continuous long-term monitoring of RVSP and ePAD is the only way for reliable detection and treatment of right ventricular hypertension, PH and consecutive changes in RVEF.
Journal: Pulmonary Circulation
DOI: 10.1002/pul2.12179
Type:
Retrospective, single center study
N:
39
2022 – CorLog publication
Monitoring of Right Ventricular Failure with Daily Pressure-Volume Loops Obtained via an App and
Three-Dimensional Echocardiography
CorLog related summary: In our opinion, the described method is an elegant and promising approach for monitoring
RV function and response to treatment by PV loop analysis. PV loops can be created at will
by performing three-dimensional echocardiography, avoiding further invasive procedures for
the patient.
Journal: Circulation: Heart Failure
DOI: 10.1161/CIRCHEARTFAILURE.122.010097
Type:
Case report
N:
1
2022
Elucidating the Clinical Implications and Pathophysiology of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction: A Call to Action
CorLog related summary: PH-HFpEF is a growing epidemic with high morbidity and mortality and no treatment. The clear unmet need and lethal nature of PH-HFpEF must be met with novel solutions at all levels of therapeutic development.
Journal: Circulation
Type:
Science Advisory
N:
–
2022
Exercise testing in heart failure with preserved ejection fraction: an appraisal through diagnosis, pathophysiology and therapy
CorLog related summary: In HFpEF, exercise intolerance is a hallmark manifestation, characterized by impairment in the physiological reserve capacity of multiple organ systems that is the cardiac dynamics itself and/or related comorbid conditions and extracardiac factors. The relative cardiac and extracardiac deficits vary among individuals. Therefore, detailed measurements made during exercise are necessary to identify and rank-order the multiorgan system limitations in exercise reserve capacity.
Journal: European Journal of Heart Failure
DOI: 10.1002/ejhf.2601
Type:
Clinical consensus statement
N:
–
2021 – CorLog publication
Continuous long-term wireless measurement of right ventricular pressures and estimated diastolic pulmonary artery pressure in patients with severe COVID-19 acute respiratory distress syndrome
CorLog related summary: Thus, insertion of an ultrathin probe into the right ventricle seems to be the only way of continuous long-term monitoring of right ventricular and pulmonary artery pressures for reliable detection and treatment of right ventricular hypertension and PAH.
Journal: ESC HF
DOI: 10.1002/ehf2.13600
Type:
Retrospective, single center study
N:
30
2020
Mechanics of right ventricular dysfunction in pulmonary arterial hypertension and heart failure with preserved ejection fraction
CorLog related summary: RV dysfunction is an independent determinant on survival in patients with all forms of PH.
Journal: Cardiovascular diagnosis and therapy
DOI: 10.21037/cdt-20-479
Type:
Meta analysis
N:
3300
2020
Complete Hemodynamic Profiling With Pulmonary Artery Catheters in Cardiogenic Shock Is Associated With Lower In-Hospital Mortality
CorLog related summary: Use of complete PAC-derived hemodynamic data prior to MCS initiation is associated with improved survival from CS.
Journal: JACC – Heart Failure
DOI: 10.1016/j.jchf.2020.08.012
Type:
Retrospective, multicenter
N:
1414
2019
Right heart failure in pulmonary hypertension: Diagnosis and new perspectives on vascular and direct right ventricular treatment
CorLog related summary: In patients with pulmonary hypertension, the adaptation of the right ventricle to the increase in afterload (RV–arterial coupling) is a key determinant of outcome. […] Given the prognostic relevance of RV–arterial coupling in pulmonary hypertension, simplified methods to assess RV–arterial coupling should be validated and incorporated into routine clinical follow-up and future clinical trials.
Journal: British Journal of Pharmacology
DOI: 10.1111/bph.14866
Type:
Meta analysis
N:
–
2017
Intracardiac Pressures Measured Using an Implantable Hemodynamic Monitor
CorLog related summary: Baseline ePAD is a predictor of mortality, independent of other covariates that have previously been demonstrated to predict mortality. Change in ePAD, from baseline to 6 months was associated with changes in subsequent mortality rate; this relationship is durable.
Journal: Circulation – Heart Failure
DOI: 10.1161/CIRCHEARTFAILURE.116.003594
Type:
Prospective, randomized, multicenter
N:
790
2013
Accuracy and precision of echocardiography versus right heart catheterization for the assessment of pulmonary hypertension
CorLog related summary: Doppler echocardiography allows for accurate measurements of the pulmonary circulation, but with moderate precision, which explains why the procedure is valid for population studies but cannot be used for the individual diagnosis of pulmonary hypertension.
Journal:International Journal of Cardiology
DOI: 10.1016/j.ijcard.2013.07.005
Type:
Prospective, single center study
N:
152
2005
Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness
CorLog related summary: Median indwelling time of pulmonary arterial catheters was 1.9 days.
Journal: JAMA
DOI: 10.1001/jama.294.13.1625
Type:
Prospective, randomized, multicenter
N:
433
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