A study on the biventricular response to positive end-expiratory pressure (PEEP) in swine, using beat-to-beat pressure waveform analysis, was published in Anesthesiology. See DOI: 10.1097/ALN.0000000000005363.
The findings demonstrate that increasing PEEP impairs right ventricular function by increasing afterload while preserving left ventricular function, with effects becoming more pronounced at higher PEEP levels. The study suggests that continuous beat-to-beat pressure-based analysis using emka algorithms could serve as a practical bedside alternative for monitoring PEEP-related hemodynamic changes.
We congratulate Joaquin D. Araos, Felix Glocker, Clark G. Owyang, Felipe Teran, Jiwon Kim, Gary Nieman, and Paul M. Heerdt on this important contribution to critical care research.